The C-peptide Signaling

The C-peptide Signaling

For years an assumption was made that C-peptide, a byproduct of insulin biosynthesis, possessed no appreciable physiologic role. As other contributions in this volume amply testify, the time has come to re-evaluate that notion. C-peptide either directly through interaction with its specific cell-surface receptor or indirectly through an interaction with a related membrane entity, exerts a uniqu...

Peptide Signaling

The study of peptide signaling is yielding both fascinating and valuable information regarding bacterial biofilm development and helping to elucidate the disease processes caused by several human pathogens. Peptide signaling potentially impacts all stages of the biofilm “life-cycle” for many bacterial species, from attachment to maturation and detachment. While the particular roles of the signa...

[C-peptide].

The C2238 Atrial Natriuretic Peptide Molecular Variant is Associated with Endothelial Damage and Dysfunction Through Natriuretic Peptide Receptor C Signaling

IRCCS Neuromed, Pozzilli, Italy; William Harvey Heart Centre, Barts & The London School of Medicine & Dentistry, London, UK; Cardiovascular Center OLV Hospital, Aalst, Belgium; Dept. of Clinical and Molecular Medicine, School of Medicine and Psychology, University Sapienza of Rome, Ospedale S. Andrea, Rome, Italy; Dept. of Pharmacological and Biomolecular Sciences, University of Milan; and Dept...

Peptide signaling in plants.

I plants, only a few peptides have been identified that act as signaling molecules (1). In contrast, signaling peptides are major players in all aspects of the life cycle in animals and yeast (2), suggesting that signaling mechanisms across the eukaryotic kingdom are fundamentally different. In animals and yeast, signaling peptides are synthesized, in general, as part of longer biologically ina...